The Correlation between the Seric Level of the Transaminases and the Degree of Hepatic Fibrosis in the Chronic Viral Hepatitis
نویسنده
چکیده
Cuvinte cheie: hepatita cronică virală, fibroza hepatică, puncţie biopsie hepatică, ALAT, ASAT Rezumat: Reacţia fibrogenică este consecinţa mecanismelor imunologice desfăşurate în prezenţa virusului care are influenţă asupra fibrogenezei. Scopul studiului a fost de a observa dacă există o legătură între modificările histologice şi valorile crescute ale ALAT şi ASAT. În acest studiu toţi pacienţii au avut un anumit grad de fibroză, fapt explicat prin simptomatologia subiectivă uşoară a bolii şi lipsa unor teste fiabile pentru descoperirea fibrozei în afară de biopsia hepatică. Raportul ASAT/ALAT a fost <1 la toate cazurile. Conform rezultatelor obţinute indicele de activitate histologică este în corelaţie cu gradul de fibroză, valorile serice ASAT şi ALAT sunt semnificative în raport cu gradul de fibroză, ele putând fi recomandate în urmărirea tratamentului de regresie a fibrozei sub tratament.
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تاریخ انتشار 2011